Monday, June 24, 2013

Multiple Sclerosis, MS and sex- Lets talk about it.........

Sex and marriage is a conversation piece in itself.  Sex and multiple sclerosis opens up a whole new can of worms. Now we are talking about function, sensation and mental motivation.

 

Being that I am in my forties, prime menopausal time and without a uterus for the past five years due to a hysterectomy, one would conclude that those factors alone would lead to an absentee sex drive.  Then add on the antidepressants , who's known side effects are just that and it seems like a losing battle.  But its not.  And when it comes to matters of intimacy, which I feel are important in a strong marriage, its important to not give up, although it seems to be the easier route.

 

Let me point out immediately, that there are far and few days that I ever feel "horny", as my husband would put it.  But women and men operate on a different sexual level.  In my own belief and personal experience, sex for a women starts in her brain, then travels to her vagina.  Perhaps this is true for an older man with compromised sensations in his crotch as well.  Even without MS, as we age our neurons aren't firing as strongly as we would like.  Also, let me add that there hasn't been a female version of viagra made available as of yet. 

 

So there are two issues here that need to be addressed- the physical crotch area and the mind. 

 

Lets start with the physical, because we are limited to some degree with options.  SO you have a vagina or penis, but unless that is pointed out to you, it goes unnoticed physically.  You need to find a counteractive solution.  What will make you "feel" your genitalia once again?  They have come out with all types of sex creme's that supposedly work as a stimulant to those areas....never worked for me, as a matter of fact , one of the last ones which I tried actually gave me irritation for several days to follow.

 

 What has worked for me as a female? Wellbutrin, or anything with a stimulant effect such as provigil.  I recall back in my days of college snorting cocaine for finals and the stimulant effect made me very susceptible to "horniness".  I'm not proud to admit that I did that, but it was over two decades ago as an invincible youth.  But the point being made that stimulants that ARE PRESCRIBED by your doctor may have the same effect on your sexuality for you as they did for me.  As a matter of fact wellbutrin came as a suggestion from my doctor to combat the sexual side effects of the luvox that I take for anxiety attacks.  But here's the downfall for me regarding stimulants.  Aside from having a heightened sexual drive, I can NOT stand the way I feel on them.  Sex only lasts a short time- maybe minutes in my own encounters but the remains of the stimulant effect lasts an entire 24 hour period. There is nothing worse for me then to feel like my mind is racing and I've just consumed 16 cups of coffee.  And that's probably the amount of coffee you would need to get the same effect.  However, others handle stimulants quite well. Its a personal experience type of scenario.  Wellbutrin also may work differently on each indivisual, as it is also an antidepressant, one known for those side effects.  Aderol also can have the same benefits as reported to me by two friends with Attention deficit disorder. Vulnerably I would also like to add that marijuana in a very limited use setting; such as two or three puffs totally re-introduces you to your crotch.  Its sort of like "HELLO-Remember me>"".  Its magical, and the orgasm is quite enhanced due to the thc properties. Because I suffer from panic attacks occasionally I have learned the hard way that 3 tokes is sufficient and don't recommend anymore. Pot enhances any feeling - good or bad.

 

Mentally, your current state of mind is important - First, I would like to express that since switching to tecfidera, bg-12 i do feel that there is less stress in my MS world due to the drugs mildness in side effects.  A clearing of the mind is also important, sort of like a meditation, leaving it open and less diluted from the immediate concerns of everyday living.  Once your mind is at ease you can train yourself to divulge in fantasy and if you are even braver turn those fantasies into realities,  You see , sex just like any other activity or event needs to be one-upped to keep interest.  Your not programmed to look forward to repetition.  Think back to the days where you went to first base and reminiscing the following few days led to arousal.  Then you went to third base and took second base for granted, the excitement was gone.  Home run, and there was no going backwards.  Now look where you are today- progression is needed. Its human nature and once again this is where your imagination comes to play- no guilt; just gust.  So pull out those handcuffs, buy yourself a magic wand-the BEST vibrator on the market, learn to talk fetish tongue, dress sexy and get crazy.  You only have one life and one genitalia- live it up.

Thursday, June 13, 2013

Tuesday, June 11, 2013

Multiple Sclerosis Research: Inhibiting T cells in MS

Multiple Sclerosis Research: Inhibiting T cells in MS: Epub :  Quach et al. CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients.  Mult Scler. 201...

Sunday, June 9, 2013

tecfidera (bg12 update - 3 weeks in, side effects and none.....


So here's my 3 week in update on tecfidera (bg12). Lets begin with flushing. The flushing was much more apparent in the first week and barely noticeable now. If I am flushing I recognize it by a brief runny nose, similar to niacins effect on me personally. Niacin however is much more harsh and the flushing on niacin in my personal experience is one hundred times stronger.


Stomach upsetting side effects have not been a symptom that I have experienced yet although I did one evening have a belly ache three days into augmentin treatment for a sinus infection. Coincedentally I aquired an upper respitory infection 3 days into my dosing and was immediately placed on augmentin which in itself causes the same symptom of stomach disturbance. I am certain that it wasn't bg12-tecfidera,or a decreased white blood cell count that caused me to fall ill, because the rest of my household fell prey to the same bug which was introduced to us by my notoriously sick preschool goddaughter.
One thing that I will say that has become a drastic improvement with the BG 12 treatment is in my bladder function. I never associated waking up in the early am hours like 5 am daily to urinate with ms. Actually I thought it was a sign of old age and have heard my mother complain of this for years. But since I began this therapy I have not once woken up to empty my bladder. Perhaps that's part of the anti-inflammatory properties. The tingling in my left arm dissipated as well even when I feel stress. This is all good stuff so far ......fingers crossed
 
One of my greatest concerns initially when taking this drug was interactions with other ones. Its so new here in the USA, and its not like we can pick up the phone and call a skin/psoriasis doctor in Germany to ask these questions..... So with experience I can tell you whats ok so far with my own trials and tribulations. For me that is. Let me run a list of drugs sampled while on tecfidera. Obviously you should check with your doctor , as im not in the medical field, holding only a degree in MS survival from the university of life experience.
 
xanax- .25 mgs at night for sleep
fluvoxemine - 50mgs hmmm, not depressed, guess i use it to retain the extra 20 pounds it initially put on my hips and belly.
augmentin - sinus infection
advil - liquid gell
magnesium
vitamin b d,c,and omega
elderberry occasionally
Hope you found this helpful, because being a crash test dummy for a newly marketed drug can be a very scary proposition! Off I go to swallow my daily vitamins since I neglected breakfast this am......
 
 

Friday, June 7, 2013

Up and coming new MS superior drug!!! Knock on wood......

Immune Boosting Therapy for Multiple Sclerosis May Be the 'Holy Grail'

Researchers claim a new therapy that protects myelin is a big breakthrough for multiple sclerosis, but patients shouldn't expect a new treatment option any time soon.



Immune Boosting Therapy for Multiple Sclerosis May Be the 'Holy Grail'




WEDNESDAY, June 5, 2013 — A groundbreaking multiple sclerosis treatment has passed a major test in its journey towards helping the two million plus living with the autoimmune disease, according to a study from Northwestern Medicine Research.
A phase 1 trial tested the new therapy which manipulates the white blood cells of MS patients and resets their immune systems. The first test on humans successfully reduced the immune systems’ reactivity to myelin – an insulating layer that protects the spinal cord, brain, and optic nerve – from 50 to 75 percent.
The destruction of myelin, a reaction caused by MS, disrupts communication from the brain to the rest of the body, and causes symptoms like mild limb numbness, paralysis, and blindness.
Similar therapies have proved to be effective for treating MS, but have also come with severe side effects because they weaken the immune system even more. While MS progression might be stopped, a weakened immune system can lead to infections and higher rates of cancer.

"Very few investigators are trying therapies in humans aimed at simply turning off unwanted immune responses and leaving the rest of the immune system intact to fight infections — to do surveillance against cancer," Dr. Lawrence Steinman, a professor of neurology at Stanford University, told HealthDay. "The early results show encouragement."
Researchers agreed that these findings, while preliminary, could have a large impact.
"The therapy stops autoimmune responses that are already activated and prevents the activation of new autoimmune cells," said Stephen Miller, the Judy Gugenheim Research Professor of Microbiology-Immunology at Northwestern University Feinberg School of Medicine, in a press release. "Our approach leaves the function of the normal immune system intact. That's the holy grail."

The Reliability of Phase 1 Trials for MS

The trial is a promising sign for the future of MS treatment, but it did have a few limitations. The Northwestern University study only included nine participants. Small samples are typically associated with phase 1 trials, but can still cause problems for the reliability of the results.
Researchers determined that the sample was not large enough to reach statistical significance for preventing the progression of MS. However, the trial did show that higher doses of white blood cells prevented some of the destruction of myelin, and there were no serious side effects reported.
For now, multiple sclerosis patients have some reason for optimism.
“The study was small – but important factors were observed,” said Trevis Gleason, an Everyday Health Leader. “The research is deserving of our attention as researchers now raise funds and recruit for Phase II trials.”
A phase 2 trial will explore how effective the therapy is in newly diagnosed patients, and will expand the sample size for further evaluation.

Saturday, June 1, 2013

Wishful thinking.....or not? Is it DEFINATELY an MS diagnosis?

Im sure many MS sufferers at one point in time thought "why me?" , or could this potentially be a wrong diagnosis?  So having both those thoughts at one time i googled around and this is what i found.

http://www.unitedspinal.org/msscene/2009/12/08/disorders-that-mimic-multiple-sclerosis/

If you do glance over the article, I'm sure you concur that the choices aren't much better.  So for the meantime IL take what i have.  And work with it the best that I can.  Although I'm not the healthiest person in the world I do believe that a little of a lot makes a huge difference.  In other words do what you can do, stop what you are able to that's negative and add some more positive to that equation.

These have been my latest changes for the better...

I use NIC-OUT filters on my cigarettes (they do not change the flavor and they remove 90% of the tar and nicotine. (AND YES I WILL QUIT ONE DAY!!)

I forcefully drink one shot of apple cider vinegar daily. I swear it helps with the tingling.... (both this and nic out can be purchase on amazon)

I QUIT my pepsi....only allow it on special occasions...

I started taking magnesium, and if anything i DON'T ever have to worry about constipation!

I have a cup or 2 of Green tea daily even though I don't love it

I inhale 95 % oxygen from a can (i get this on amazon too)

An I take my immune boost drink  7 days out of the month

The next goal is to start cardio up again....and yoga can NEVER be underestimated.  I personally met someone at a MS conference who went from wheelchair to marathons due to yoga.